ABSTRACT
Abstract INTRODUCTION: In most Strongyloides stercoralis infected individuals, nematoidosis occurs asymptomatically, but in immunocompromised patients, it can cause hyperinfection. Serological techniques seem to be a good alternative for detecting this parasite. METHODS The frequency of seropositivity for strongyloidiasis in Alfenas, MG, was estimated using the enzyme linked immunosorbent assay on blood samples, between May and August of 2015. RESULTS: Out of 258 samples tested, 53.9% were positive, and the frequency of seropositive individuals was higher in the peripheral districts of the municipality. CONCLUSIONS: The results indicate high seropositivity rates for strongyloidiasis among the residents of Alfenas city.
Subject(s)
Humans , Animals , Male , Female , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Aged , Young Adult , Strongyloidiasis/epidemiology , Antibodies, Helminth/blood , Strongyloides stercoralis/immunology , Strongyloidiasis/diagnosis , Strongyloidiasis/transmission , Brazil/epidemiology , Immunoglobulin G/blood , Enzyme-Linked Immunosorbent Assay , Seroepidemiologic Studies , Middle AgedABSTRACT
The objective of this study was to determine the presence of Strongyloides stercoralis in urban garbage collectors through the use of immunological and parasitological methods. A total of 92 individuals were evaluated from August, 1997, to June, 1998. For the parasitological diagnosis Baermann and Lutz' methods were applied. The immunological diagnosis involved the indirect fluorescence antibody test (IFAT) and the enzyme-linked immunosorbent assay (ELISA) to detect specific IgG antibodies. Of the 92 workers examined, six (6.5 percent) were infected with larvae of S. stercoralis. The IFAT detected 19 (16.3 percent) and the ELISA 17 (18.5 percent) positive serum samples. The differences between the results of parasitological and immunological methods were statistically significant (p<0.05). These results demonstrate that there is a need to improve the health conditions of this category of city employees.
Subject(s)
Humans , Animals , Male , Female , Adult , Middle Aged , Occupational Diseases/parasitology , Strongyloidiasis/diagnosis , Strongyloidiasis/epidemiology , Garbage , Strongyloides stercoralis/immunology , Age and Sex Distribution , Antibodies, Helminth/analysis , Brazil , Enzyme-Linked Immunosorbent Assay , Occupational Diseases/diagnosis , Strongyloidiasis/immunology , Strongyloidiasis/transmission , Fluorescent Antibody Technique, Indirect , Immunoglobulin G/analysis , Occupational Exposure , Intestinal Diseases, Parasitic/epidemiology , Strongyloides stercoralis/isolation & purification , Strongyloides stercoralis/growth & developmentSubject(s)
Humans , Giardiasis/prevention & control , Intestinal Diseases, Parasitic/prevention & control , Ancylostomiasis/transmission , Giardiasis/epidemiology , Giardiasis/transmission , Hymenolepiasis/transmission , Intestinal Diseases, Parasitic/epidemiology , Oxyuriasis/prevention & control , Oxyuriasis/transmission , Strongyloidiasis/transmission , Toxocariasis/prevention & control , Toxocariasis/transmissionABSTRACT
A estrongiloidiase e uma doenca parasitaria de distribuicao mundial e de grande importancia no Brasil. Entre as diversas especies existentes do genero Strongyloides, apenas o S. stercoralis, o S. fulleborni e o S. fulleborni-like tem importancia para o homen. Embora o S. stercoralis seja um helminto intestinal, a estrongiloidiase e uma infeccao sistemica, podendo acometer alem do trato gastrointestinal, os pulmoes, SNC, figado e vias biliares, pancreas, trato genitourinario e pele. Na maioria dos casos, a estrongiloidiase e assintomatica, de curso cronico e benigno. Os sintomas gastrointestinais e pulmonares sao os mais importantes entre os casos assintomaticos. Por motivos ainda nao muito bem compreendidos, a infeccao pelo estrongiloides pode resultar em doenca severa e disseminada. O uso de terapia imunossupressora foi identificado como fator de risco importante para a forma disseminada nos paises industrializados. O diagnostico da estrongiloidiase pode ser dificil, e embora o exame parasitologico de fezes seja o mais utilizado nem sempre sao identificados larvas do parasito...
Subject(s)
Humans , Strongyloidiasis/diagnosis , Strongyloides/classification , Enzyme-Linked Immunosorbent Assay , Strongyloidiasis/classification , Strongyloidiasis/immunology , Strongyloidiasis/parasitology , Strongyloidiasis/therapy , Strongyloidiasis/transmission , Strongyloides/pathogenicity , Thiabendazole/therapeutic useABSTRACT
La estrongiliodiasis diseminada (ED) es una afeccion frecuentemente fatal debida a la autoinfeccion interna con larvas de Strongiliodes stercoralis, oportunista ante alteracions de la inmunidad del huesped, como inmunosupresion farmacologica en pacientes transplantados o con enfermedad neoplasica o autoinmune. Revisamos la ED en los archivos de autopsias del Hospital San Juan de Dios y la Misericordia de Bogota para conocer la entidad basica facilitadora de la diseminacion larvaria y averiguar si la ED ha aumentado recientemente. Se encontraron solo 12 enfermos en mas de 14000 protocolos revisados desde 1954 a 1986 con edades entre 1 y 62 anos. Los pacientes presentaron diarrea cronica, fetida o sanguinolenta, vomito, dolor abdominal, anorexia y tos, a veces hemoptoica. Todos tenian desnutricion avanzada y solo uno habia recibido tratamiento inmunosupresor con esteriodes y ciclofosfamida para glomerulonefritis progresiva. Un paciente recibio esteriodes para "colitis ulcerativa" que luego se comprobo era debida a estrongiloidiasis. Solo una vez se hizo diagnostico clinico de ED. En tres pacientes se encontraron larvas en la materia fecal pero no se considero la posibilidad de ED. Los diagnosticos clinicos considerados fueron: desnutricion, sindrome anemico, carcinoma gastrico, TBC pulmonar e intestinal, parasisitismo y sindrome meningeo. Una enferma presento endocarditis bacteriana tricuspidea y dos miningoencefalitis, unidas al cuadro gastrointestinal. La meningitis fue de tipo bateriano, aguda, sin granulomas ni larvas